Add bio.helena-folklore

[vladimir-mitev]

Summary

Registers the hosted Streamable HTTP endpoint with its existing connection schema; updates the discovery description.

Current Folklore MCP release: 1.5.0. Bioinformatics MCP for genomic variant interpretation, gene-disease evidence and literature.

Public connection and capabilities

• Endpoint: https://api.helena.bio/folklore/v1/mcp (Streamable HTTP; no account or API key).
• Source: https://github.com/helena-bioinformatics/folklore-mcp
• Connection guide: https://folklore.helena.bio/integrations
• Registry identity: io.github.helena-bioinformatics/folklore
• Release: https://github.com/helena-bioinformatics/folklore-mcp/releases/tag/folklore-mcp-v1.5.0

The live endpoint exposes seven tools:

1. search_variant_evidence
2. search_variant_literature
3. get_publication_details
4. search_literature_corpus
5. support_helena (separate optional support discovery)
6. get_gene_disease_associations
7. search_disease_genes

The two new scientific tools return ClinGen Gene-Disease Validity assertions by exact gene symbol/HGNC ID or MONDO ID/disease-name search. They preserve distinct disease identities, inheritance, source classifications, reports and snapshot provenance. Existing variant and literature tools are retained; this release does not change the variant classifier.

Scope and validation

Variant interpretation is limited to supported GRCh38 germline variants. Gene-disease validity is not individual variant pathogenicity or a patient diagnosis. No raw DNA/VCF ingestion, batch variant processing, patient symptoms or private case data. Results require qualified professional review.

The upstream release and live seven-tool catalogue were verified on 2026-09-11. This confirms the hosted service, not acceptance or complete compatibility testing by this project. Refer to this pull request's checks and current diff for project-specific validation.